Medical Dictionary

progressive multifocal leukoencephalopathy

noun

Medical Definition of PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

:  a progressive and fatal demyelinating disease of the central nervous system that typically occurs in immunosuppressed individuals due to loss of childhood immunity to a double-stranded DNA virus of the genus Polyomavirus (species JC polyomavirus) ubiquitous in human populations and that is characterized by hemianopia, hemiplegia, alterations in mental state, and eventually coma

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